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Conserved nematode signalling molecules elicit plant defenses and pathogen resistance

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Title Conserved nematode signalling molecules elicit plant defenses and pathogen resistance
 
Creator Manosalva, Patricia
Manohar, Murli
von Reuss, Stephan H.
Chen, Shiyan
Koch, Aline
Kaplan, Fatma
Choe, Andrea
Micikas, Robert J.
Wang, Xiaohong
Kogel, Karl-Heinz
Sternberg, Paul W.
Williamson, Valerie M.
Schroeder, Frank C.
Klessig, Daniel F.
 
Description Plant-defense responses are triggered by perception of conserved microbe-associated molecular patterns (MAMPs), for example, flagellin or peptidoglycan. However, it remained unknown whether plants can detect conserved molecular patterns derived from plant-parasitic animals, including nematodes. Here we show that several genera of plant-parasitic nematodes produce small molecules called ascarosides, an evolutionarily conserved family of nematode pheromones. Picomolar to micromolar concentrations of ascr#18, the major ascaroside in plant-parasitic nematodes, induce hallmark defense responses including the expression of genes associated with MAMP-triggered immunity, activation of mitogen-activated protein kinases, as well as salicylic acid- and jasmonic acid-mediated defense signalling pathways. Ascr#18 perception increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections. These results indicate that plants recognize ascarosides as a conserved molecular signature of nematodes. Using small-molecule signals such as ascarosides to activate plant immune responses has potential utility to improve economic and environmental sustainability of agriculture.
 
Publisher Nature Publishing Group
 
Date 2015-07
 
Type Article
PeerReviewed
 
Format application/pdf
application/pdf
 
Identifier http://authors.library.caltech.edu/59788/1/ncomms8795.pdf
http://authors.library.caltech.edu/59788/2/ncomms8795-s1.pdf
Manosalva, Patricia and Manohar, Murli and von Reuss, Stephan H. and Chen, Shiyan and Koch, Aline and Kaplan, Fatma and Choe, Andrea and Micikas, Robert J. and Wang, Xiaohong and Kogel, Karl-Heinz and Sternberg, Paul W. and Williamson, Valerie M. and Schroeder, Frank C. and Klessig, Daniel F. (2015) Conserved nematode signalling molecules elicit plant defenses and pathogen resistance. Nature Communications, 6 (7). Art. No. 7795. ISSN 2041-1723. http://resolver.caltech.edu/CaltechAUTHORS:20150820-104302919 <http://resolver.caltech.edu/CaltechAUTHORS:20150820-104302919>
 
Relation http://resolver.caltech.edu/CaltechAUTHORS:20150820-104302919
http://authors.library.caltech.edu/59788/