Conserved nematode signalling molecules elicit plant defenses and pathogen resistance
CaltechAUTHORS
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| Title |
Conserved nematode signalling molecules elicit plant defenses and pathogen resistance
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| Creator |
Manosalva, Patricia
Manohar, Murli von Reuss, Stephan H. Chen, Shiyan Koch, Aline Kaplan, Fatma Choe, Andrea Micikas, Robert J. Wang, Xiaohong Kogel, Karl-Heinz Sternberg, Paul W. Williamson, Valerie M. Schroeder, Frank C. Klessig, Daniel F. |
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| Description |
Plant-defense responses are triggered by perception of conserved microbe-associated molecular patterns (MAMPs), for example, flagellin or peptidoglycan. However, it remained unknown whether plants can detect conserved molecular patterns derived from plant-parasitic animals, including nematodes. Here we show that several genera of plant-parasitic nematodes produce small molecules called ascarosides, an evolutionarily conserved family of nematode pheromones. Picomolar to micromolar concentrations of ascr#18, the major ascaroside in plant-parasitic nematodes, induce hallmark defense responses including the expression of genes associated with MAMP-triggered immunity, activation of mitogen-activated protein kinases, as well as salicylic acid- and jasmonic acid-mediated defense signalling pathways. Ascr#18 perception increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections. These results indicate that plants recognize ascarosides as a conserved molecular signature of nematodes. Using small-molecule signals such as ascarosides to activate plant immune responses has potential utility to improve economic and environmental sustainability of agriculture.
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| Publisher |
Nature Publishing Group
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| Date |
2015-07
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
application/pdf |
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| Identifier |
http://authors.library.caltech.edu/59788/1/ncomms8795.pdf
http://authors.library.caltech.edu/59788/2/ncomms8795-s1.pdf Manosalva, Patricia and Manohar, Murli and von Reuss, Stephan H. and Chen, Shiyan and Koch, Aline and Kaplan, Fatma and Choe, Andrea and Micikas, Robert J. and Wang, Xiaohong and Kogel, Karl-Heinz and Sternberg, Paul W. and Williamson, Valerie M. and Schroeder, Frank C. and Klessig, Daniel F. (2015) Conserved nematode signalling molecules elicit plant defenses and pathogen resistance. Nature Communications, 6 (7). Art. No. 7795. ISSN 2041-1723. http://resolver.caltech.edu/CaltechAUTHORS:20150820-104302919 <http://resolver.caltech.edu/CaltechAUTHORS:20150820-104302919> |
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| Relation |
http://resolver.caltech.edu/CaltechAUTHORS:20150820-104302919
http://authors.library.caltech.edu/59788/ |
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